Lista de indicados:

Masculino:

Justin Timberlake
Kanye West
Pharrell Williams
Robbie Williams
Sean Paul

Feminino:

Beyoncé
Christina Aguilera
Madonna
Nelly Furtado
Shakira

Grupo:

Black Eyed Peas
Depeche Mode
Keane
Pussycat Dolls
Red Hot Chili Peppers

Rock:

Evanescence
Keane
The Killers
Red Hot Chili Peppers
The Strokes
Hip Hop:

Busta Rhymes
Kanye West
Missy Elliott
P. Diddy
Sean Paul

Alternativo:

Artic Monkeys, Korn
Muse
The Raconteurs
System Of A Down

Canção:

Gnarls Barkley - 'Crazy'
Nelly Furtado - 'Maneater'
Red Hot Chili Peppers - 'Dani California'
Rihanna - 'SOS'
Shakira Ft Wyclef Jean - 'Hips Don't Lie'

R&B:

Beyoncé
Mary J. Blige
Outkast
Pharrell Williams
Rihanna

Pop:

Christina Aguilera
Justin Timberlake
Madonna
Robbie Williams
Shakira

Álbum:

Christina Aguilera - Back to Basics
Madonna - Confessions on a Dance Floor
Muse - Black Holes and Revelations
Nelly Furtado - Loose
Red Hot Chili Peppers - Stadium Arcadium

Videoclipe:

Gnarls Barkley - 'Crazy'
Justice Vs Simian - 'We Are Your Friends'
Kanye West - 'Touch The Sky'
Ok Go - 'A Million Ways'
Pink - 'Stupid Girls'

Melhor do Reino Unido e Irlanda

Arctic Monkeys
Corrine Bailey Rae
Lily Allen
Muse
The Kooks